Alprenolol Explained

Alprenolol, or alfeprol, alpheprol, and alprenololum (Gubernal, Regletin, Yobir, Apllobal, Aptine, Aptol Duriles), is a non-selective beta blocker as well as a 5-HT1A and 5-HT1B receptor antagonist,[1] used in the treatment of angina pectoris.[2] It is no longer marketed by AstraZeneca, but may still be available from other pharmaceutical companies or generically.

Notes and References

  1. Langlois M, Brémont B, Rousselle D, Gaudy F . Structural analysis by the comparative molecular field analysis method of the affinity of beta-adrenoreceptor blocking agents for 5-HT1A and 5-HT1B receptors . Eur. J. Pharmacol. . 244 . 1 . 77–87 . 1993 . 8093601 . 10.1016/0922-4106(93)90061-d.
  2. Hickie JB. 1970. Alprenolol ("aptin") in angina pectoris. A double-blind multicentre trial. Med. J. Aust.. 2. 6. 268–72. 10.5694/j.1326-5377.1970.tb49984.x. 4393977. 6879318.

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