Alpha-D-xyloside xylohydrolase explained

Alpha-D-xyloside xylohydrolase
Ec Number:	3.2.1.177

Alpha-D-xyloside xylohydrolase (alpha-xylosidase) is an enzyme.^{[1] [2] [3] [4] [5] [6] [7]} This enzyme catalyses the following chemical reaction

Hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose.

The enzyme catalyses hydrolysis of a terminal, unsubstituted xyloside at the extreme reducing end of a xylogluco-oligosaccharide.

Notes and References

1. Moracci M, Cobucci Ponzano B, Trincone A, Fusco S, De Rosa M, van Der Oost J, Sensen CW, Charlebois RL, Rossi M . Identification and molecular characterization of the first alpha -xylosidase from an archaeon . The Journal of Biological Chemistry . 275 . 29 . 22082–9 . July 2000 . 10801892 . 10.1074/jbc.M910392199 . free .
2. Sampedro J, Sieiro C, Revilla G, González-Villa T, Zarra I . Cloning and expression pattern of a gene encoding an alpha-xylosidase active against xyloglucan oligosaccharides from Arabidopsis . Plant Physiology . 126 . 2 . 910–20 . June 2001 . 11402218 . 111180 . 10.1104/pp.126.2.910 .
3. Crombie HJ, Chengappa S, Jarman C, Sidebottom C, Reid JS . Molecular characterisation of a xyloglucan oligosaccharide-acting alpha-D-xylosidase from nasturtium (Tropaeolum majus L.) cotyledons that resembles plant 'apoplastic' alpha-D-glucosidases . Planta . 214 . 3 . 406–13 . January 2002 . 11859845 . 10.1007/s004250100631 .
4. Lovering AL, Lee SS, Kim YW, Withers SG, Strynadka NC . Mechanistic and structural analysis of a family 31 alpha-glycosidase and its glycosyl-enzyme intermediate . The Journal of Biological Chemistry . 280 . 3 . 2105–15 . January 2005 . 15501829 . 10.1074/jbc.m410468200 . free .
5. Iglesias N, Abelenda JA, Rodiño M, Sampedro J, Revilla G, Zarra I . Apoplastic glycosidases active against xyloglucan oligosaccharides of Arabidopsis thaliana . Plant & Cell Physiology . 47 . 1 . 55–63 . January 2006 . 16267099 . 10.1093/pcp/pci223 . free .
6. Okuyama M, Kaneko A, Mori H, Chiba S, Kimura A . Structural elements to convert Escherichia coli alpha-xylosidase (YicI) into alpha-glucosidase . FEBS Letters . 580 . 11 . 2707–11 . May 2006 . 16631751 . 10.1016/j.febslet.2006.04.025 .
7. Larsbrink J, Izumi A, Ibatullin FM, Nakhai A, Gilbert HJ, Davies GJ, Brumer H . Structural and enzymatic characterization of a glycoside hydrolase family 31 α-xylosidase from Cellvibrio japonicus involved in xyloglucan saccharification . The Biochemical Journal . 436 . 3 . 567–80 . June 2011 . 21426303 . 10.1042/bj20110299 . Harry J. Gilbert . Gideon Davies .