Α-Cyano-4-hydroxycinnamic acid explained

α-Cyano-4-hydroxycinnamic acid, also written as alpha-cyano-4-hydroxycinnamic acid and abbreviated CHCA or HCCA, is a cinnamic acid derivative and is a member of the phenylpropanoid family. The carboxylate form is α-cyano-4-hydroxycinnamate.

Matrix-assisted laser desorption/ionization

α-Cyano-4-hydroxycinnamic acid is used as a matrix for peptides and nucleotides in MALDI mass spectrometry analyses.^{[1] [2]}

See also

• Sinapinic acid

Notes and References

1. -α-Cyano-4-hydroxycinnamic acid as a matrix for matrix-assisted laser desorption mass spectrometry . Org. Mass Spectrom. . 27 . 2. 156–8 . 1992 . 10.1002/oms.1210270217 . Beavis, R. C. . Chaudhary . T. . Chait . B. T..
2. Book: Franz Hillenkamp. Jasna Peter-Katalinic. MALDI MS: A Practical Guide to Instrumentation, Methods and Applications. 3 October 2013. Wiley. 978-3-527-67373-5. 110–.