Alpha,alpha-trehalose synthase explained

Alpha,alpha-trehalose synthase
Ec Number:2.4.1.245

Alpha,alpha-trehalose synthase (trehalose synthase, trehalose synthetase, UDP-glucose:glucose 1-glucosyltransferase, TreT, PhGT) is an enzyme with systematic name ADP-glucose:D-glucose 1-alpha-D-glucosyltransferase.[1] [2] This enzyme catalyses the following chemical reaction

\rightleftharpoons

alpha,alpha-trehalose + ADP

This enzyme requires Mg2+ for maximal activity.

Notes and References

  1. Qu Q, Lee SJ, Boos W . TreT, a novel trehalose glycosyltransferring synthase of the hyperthermophilic archaeon Thermococcus litoralis . The Journal of Biological Chemistry . 279 . 46 . 47890–7 . November 2004 . 15364950 . 10.1074/jbc.m404955200 . free.
  2. Ryu SI, Park CS, Cha J, Woo EJ, Lee SB . A novel trehalose-synthesizing glycosyltransferase from Pyrococcus horikoshii: molecular cloning and characterization . Biochemical and Biophysical Research Communications . 329 . 2 . 429–36 . April 2005 . 15737605 . 10.1016/j.bbrc.2005.01.149 .

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