All-trans-retinyl ester 13-cis isomerohydrolase explained

all-trans-Retinyl ester 13-cis isomerohydrolase
Ec Number:	3.1.1.90

The enzyme all-trans-retinyl ester 13-cis isomerohydrolase (EC 3.1.1.90; systematic name all-trans-retinyl ester acylhydrolase, 13-cis retinol forming^[1] catalyses the reaction

an all-trans-retinyl ester + H₂O

\rightleftharpoons 13-cis-retinol + a fatty acid

Notes and References

1. Takahashi Y, Moiseyev G, Chen Y, Farjo K, Nikolaeva O, Ma JX . An enzymatic mechanism for generating the precursor of endogenous 13-cis retinoic acid in the brain . The FEBS Journal . 278 . 6 . 973–87 . April 2011 . 21235714 . 3073448 . 10.1111/j.1742-4658.2011.08019.x .