All-trans-octaprenyl-diphosphate synthase explained
| All-trans-octaprenyl-diphosphate synthase |
| Ec Number: | 2.5.1.90 |
All-trans-octaprenyl-diphosphate synthase (octaprenyl-diphosphate synthase, octaprenyl pyrophosphate synthetase, polyprenylpyrophosphate synthetase, terpenoidallyltransferase, terpenyl pyrophosphate synthetase, trans-heptaprenyltranstransferase, trans-prenyltransferase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 5 isopentenyl units).[1] [2] This enzyme catalyses the following chemical reaction
5
diphosphate + all-trans-octaprenyl diphosphate
This enzyme catalyses the condensation reactions resulting in the formation of all-trans-octaprenyl diphosphate.
Notes and References
- Fujisaki S, Nishino T, Katsuki H . Isoprenoid synthesis in Escherichia coli. Separation and partial purification of four enzymes involved in the synthesis . Journal of Biochemistry . 99 . 5 . 1327–37 . May 1986 . 10.1093/oxfordjournals.jbchem.a135600 . 3519603 .
- Asai K, Fujisaki S, Nishimura Y, Nishino T, Okada K, Nakagawa T, Kawamukai M, Matsuda H . The identification of Escherichia coli ispB (cel) gene encoding the octaprenyl diphosphate synthase . Biochemical and Biophysical Research Communications . 202 . 1 . 340–5 . July 1994 . 8037730 . 10.1006/bbrc.1994.1933 .
