All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) explained
| All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) |
| Ec Number: | 2.5.1.84 |
All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) (nonaprenyl diphosphate synthase, solanesyl diphosphate synthase, SolPP synthase, SPP-synthase, SPP synthase, solanesyl-diphosphate synthase, OsSPS2) is an enzyme with systematic name geranyl-diphosphate:isopentenyl-diphosphate transtransferase (adding 7 isopentenyl units).[1] [2] [3] [4] [5] [6] This enzyme catalyses the following chemical reaction
7
diphosphate + all-trans-nonaprenyl diphosphate
This enzyme is involved in the synthesis of the side chain of menaquinone-9.
Notes and References
- Sagami H, Ogura K, Seto S . Solanesyl pyrophosphate synthetase from Micrococcus lysodeikticus . Biochemistry . 16 . 21 . 4616–22 . October 1977 . 911777 . 10.1021/bi00640a014 .
- Fujii H, Sagami H, Koyama T, Ogura K, Seto S, Baba T, Allen CM . Variable product specificity of solanesyl pyrophosphate synthetase . Biochemical and Biophysical Research Communications . 96 . 4 . 1648–53 . October 1980 . 7447947 . 10.1016/0006-291X(80)91363-7 .
- Ohara K, Sasaki K, Yazaki K . Two solanesyl diphosphate synthases with different subcellular localizations and their respective physiological roles in Oryza sativa . Journal of Experimental Botany . 61 . 10 . 2683–92 . June 2010 . 20421194 . 2882263 . 10.1093/jxb/erq103 .
- Ohnuma S, Koyama T, Ogura K . Purification of solanesyl-diphosphate synthase from Micrococcus luteus. A new class of prenyltransferase . The Journal of Biological Chemistry . 266 . 35 . 23706–13 . December 1991 . 1748647 .
- Gotoh T, Koyama T, Ogura K . Farnesyl diphosphate synthase and solanesyl diphosphate synthase reactions of diphosphate-modified allylic analogs: the significance of the diphosphate linkage involved in the allylic substrates for prenyltransferase . Journal of Biochemistry . 112 . 1 . 20–7 . July 1992 . 1429508 .
- Teclebrhan H, Olsson J, Swiezewska E, Dallner G . Biosynthesis of the side chain of ubiquinone:trans-prenyltransferase in rat liver microsomes . The Journal of Biological Chemistry . 268 . 31 . 23081–6 . November 1993 . 8226825 .
