Alkylacetylglycerophosphatase Explained

alkylacetylglycerophosphatase
Ec Number:	3.1.3.59
Cas Number:	102925-45-1
Go Code:	0047647

The enzyme alkylacetylglycerophosphatase (EC 3.1.3.59) catalyzes the reaction

1-alkyl-2-acetyl-sn-glycero-3-phosphate + H₂O

\rightleftharpoons 1-alkyl-2-acetyl-sn-glycerol + phosphate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is 1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase. Other names in common use include 1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase, and alkylacetylglycerophosphate phosphatase. This enzyme participates in ether lipid metabolism.

References

• Lee TC, Malone B, Snyder F . 1986 . A new de novo pathway for the formation of 1-alkyl-2-acetyl-sn-glycerols, precursors of platelet activating factor. Biochemical characterization of 1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase in rat spleen . J. Biol. Chem. . 261 . 5373 - 7 . 3007498 . 12 .