Alcohol sulfotransferase explained

Alcohol sulfotransferase
Ec Number:	2.8.2.2
Cas Number:	9032-76-2
Go Code:	0004027

Alcohol sulfotransferase is an enzyme that catalyzes the sulfate conjugation of primary and secondary alcohols including many hormones, neurotransmitters, drugs, and xenobiotic compounds.^{[1] [2]}

The chemical reaction is:

an alcohol + 3'-phosphoadenylyl-sulfate

\rightleftharpoons adenosine 3',5'-bisphosphate + an organosulfate + H+

Family members

Human genes that encode alcohol sulfotransferases include:

• SULT2A1
• SULT2B1
• SULT1C3

See also

• sulfotransferase

Notes and References

1. Lyon ES, Jakoby WB . The identity of alcohol sulfotransferases with hydroxysteroid sulfotransferases . Arch. Biochem. Biophys. . 202 . 2 . 474–81 . July 1980 . 6935986 . 10.1016/0003-9861(80)90452-X.
2. Book: Lyon ES, Marcus CJ, Wang JL, Jakoby WB . Hydroxysteroid sulfotransferase . Detoxication and Drug Metabolism: Conjugation and Related Systems . Meth. Enzymol. . 77 . 206–13 . 1981 . 6173569 . 10.1016/S0076-6879(81)77027-7. 978-0-12-181977-4 .