Alcohol-forming fatty acyl-CoA reductase explained

Alcohol-forming fatty acyl-CoA reductase
Ec Number:	1.2.1.84

Alcohol-forming fatty acyl-CoA reductase (FAR (gene)) is an enzyme with systematic name long-chain acyl-CoA:NADPH reductase.^[1] This enzyme catalyses the following chemical reaction

a long-chain acyl-CoA + 2 NADPH + 2 H⁺

\rightleftharpoons a long-chain alcohol + 2 NADP⁺ + coenzyme A

The enzyme has been characterized from the plant Simmondsia chinensis.

Notes and References

1. Metz JG, Pollard MR, Anderson L, Hayes TR, Lassner MW . Purification of a jojoba embryo fatty acyl-coenzyme A reductase and expression of its cDNA in high erucic acid rapeseed . Plant Physiology . 122 . 3 . 635–44 . March 2000 . 10712526 . 58898 . 10.1104/pp.122.3.635 .