Brodmann area 30 explained

Brodmann area 30
Latin:	area retrosplenialis agranularis

Brodmann area 30, also known as agranular retrolimbic area 30, is a subdivision of the cytoarchitecturally defined retrosplenial region of the cerebral cortex. In the human it is located in the isthmus of cingulate gyrus. Cytoarchitecturally it is bounded internally by the granular retrolimbic area 29, dorsally by the ventral posterior cingulate area 23 and ventrolaterally by the ectorhinal area 36 (Brodmann-1909).

In primates, Brodmann area 30 demonstrates projections to the mid-dorsolateral prefrontal cortex (Brodmann areas 46 and 9) ^[1] and the thalamus.^[2] Additionally, approximately 20% of cortical inputs to the entorhinal cortex arise from the retrosplenial cortex.^[3]

Individuals with lesions to retrosplenial cortex, predominately Brodmann’s area 30, demonstrate dysfunction in their topographical orientation,^[4] including defective navigation in novel and familiar environments.

See also

• Brodmann area
• Retrosplenial cortex

Notes and References

1. Morris . Renée . Petrides . Michael . Pandya . Deepak N. . July 1999 . Architecture and connections of retrosplenial area 30 in the rhesus monkey (macaca mulatta). . European Journal of Neuroscience . 11 . 7 . 2506–2518 . 10.1046/j.1460-9568.1999.00672.x . 0953-816X.
2. Robertson . Richard T. . Kaitz . Suzan S. . 1981-01-20 . Thalamic connections with limbic cortex. I. Thalamocortical projections . Journal of Comparative Neurology . 195 . 3 . 501–525 . 10.1002/cne.901950308 . 0021-9967.
3. Insausti . R. . Amaral . D. G. . Cowan . W. M. . 1987-10-15 . The entorhinal cortex of the monkey: II. Cortical afferents . Journal of Comparative Neurology . 264 . 3 . 356–395 . 10.1002/cne.902640306 . 0021-9967.
4. Maguire . Eleanor . July 2001 . The retrosplenial contribution to human navigation: A review of lesion and neuroimaging findings . Scandinavian Journal of Psychology . 42 . 3 . 225–238 . 10.1111/1467-9450.00233 . 0036-5564.