Adipostatin A Explained

Adipostatin A is an alkylresorcinol, a type of phenolic lipids composed of long aliphatic chains and phenolic rings. Chemically, it is similar in structure to urushiol, the irritant found in poison ivy.

Adipostatin A can be found in Ginkgo biloba fruits as well as in Streptomyces cyaneus.[1] It is also found in cashew nutshell liquid (Anacardium occidentale), in Anacardium othonianum and in Ardisia elliptica.[2]

It is an inhibitor of glycerol-3-phosphate dehydrogenase.[3]

Notes and References

  1. 21462031. 2011. Tanaka. A. Arai. Y. Kim. SN. Ham. J. Usuki. T. Synthesis and biological evaluation of bilobol and adipostatin A. 13. 4. 290–6. 10.1080/10286020.2011.554828. Journal of Asian Natural Products Research. 25305504.
  2. Koh Hwee Ling, Chua Tung Kian, and Tan Chay Hoon. "A Guide to Medicinal Plants: An Illustrated, Scientific and Medicinal Approach", p. 14. World Scientific Publishing 2009, . Preview available at Google Books
  3. 1500355. 1992. Tsuge. N. Mizokami. M. Imai. S. Shimazu. A. Seto. H. Adipostatins a and B, new inhibitors of glycerol-3-phosphate dehydrogenase. 45. 6. 886–91. The Journal of Antibiotics. 10.7164/antibiotics.45.886. free.

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