Acylcarnitine hydrolase explained

acylcarnitine hydrolase
Ec Number:	3.1.1.28
Cas Number:	37278-42-5
Go Code:	0047619

The enzyme acylcarnitine hydrolase (EC 3.1.1.28) catalyzes the reaction

O-acylcarnitine + H₂O

\rightleftharpoons a fatty acid + L-carnitine

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is O-acylcarnitine acylhydrolase. Other names in common use include high activity acylcarnitine hydrolase, HACH, carnitine ester hydrolase, palmitoylcarnitine hydrolase, palmitoyl-L-carnitine hydrolase, long-chain acyl-L-carnitine hydrolase, and palmitoyl carnitine hydrolase.

References

• Mahadevan S, Sauer F . 1969 . Carnitine ester hydrolase of rat liver . J. Biol. Chem. . 244 . 4448 - 53 . 5806585 . 16 .
• Mentlein R, Reuter G, Heymann E . 1985 . Specificity of two different purified acylcarnitine hydrolases from rat liver, their identity with other carboxylesterases, and their possible function . Arch. Biochem. Biophys. . 240 . 801 - 10 . 4026306 . 10.1016/0003-9861(85)90089-X . 2 .