| acyl-CoA oxidase | |
| Ec Number: | 1.3.3.6 |
| Cas Number: | 61116-22-1 |
| Go Code: | 0003997 |
In enzymology, an acyl-CoA oxidase is an enzyme that catalyzes the chemical reaction
acyl-CoA + O2
\rightleftharpoons
Thus, the two substrates of this enzyme are acyl-CoA and O2, whereas its two products are trans-2,3-dehydroacyl-CoA and H2O2.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with oxygen as acceptor. The systematic name of this enzyme class is acyl-CoA:oxygen 2-oxidoreductase. Other names in common use include fatty acyl-CoA oxidase, acyl coenzyme A oxidase, and fatty acyl-coenzyme A oxidase. This enzyme participates in 3 metabolic pathways: fatty acid metabolism, polyunsaturated fatty acid biosynthesis, and ppar signaling pathway. It employs one cofactor, FAD.
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes,,,,, and .