Activating protein 2 explained

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
Symbol:	TFAP2A
Altsymbols:	TFAP2, AP2TF
Entrezgene:	7020
Hgncid:	11742
Omim:	107580
Refseq:	NM_003220
Uniprot:	P05549
Chromosome:	6
Arm:	p
Band:	22.3

transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
Symbol:	TFAP2B
Altsymbols:	AP2-B
Entrezgene:	7021
Hgncid:	11743
Omim:	601601
Refseq:	NM_003221
Uniprot:	Q92481
Chromosome:	6
Arm:	p
Band:	12

transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
Symbol:	TFAP2C
Entrezgene:	7022
Hgncid:	11744
Omim:	601602
Refseq:	NM_003222
Uniprot:	Q92754
Chromosome:	20
Arm:	q
Band:	13.2

transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
Symbol:	TFAP2D
Altsymbols:	TFAP2BL1
Entrezgene:	83741
Hgncid:	15581
Omim:	610161
Refseq:	NM_172238
Uniprot:	Q7Z6R9
Chromosome:	6
Arm:	p
Band:	12.3

transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
Symbol:	TFAP2E
Altsymbols:	AP2E
Entrezgene:	339488
Hgncid:	30774
Refseq:	NM_178548
Uniprot:	Q6VUC0
Chromosome:	1
Arm:	p
Band:	34.3

Activating Protein 2 (AP-2) is a family of closely related transcription factors^[1] ^[2] which plays a critical role in regulating gene expression during early development.^[3]

Notes and References

Williams T, Tjian R . Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins . Science . 251 . 4997 . 1067–71 . 1991 . 1998122 . 10.1126/science.1998122. 1991Sci...251.1067W .
Williams T, Tjian R . Analysis of the DNA-binding and activation properties of the human transcription factor AP-2 . Genes Dev. . 5 . 4 . 670–82 . 1991 . 2010091 . 10.1101/gad.5.4.670. free .
Hilger-Eversheim K, Moser M, Schorle H, Buettner R . Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control . Gene . 260 . 1–2 . 1–12 . 2000 . 11137286 . 10.1016/S0378-1119(00)00454-6.