Actinomycin lactonase explained

actinomycin lactonase
Ec Number:	3.1.1.39
Cas Number:	37288-09-8
Go Code:	0047615

The enzyme actinomycin lactonase (EC 3.1.1.39) catalyzes the reaction

actinomycin + H₂O

\rightleftharpoons actinomycinic monolactone

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is actinomycin lactonohydrolase.

References

• Hou CT, Perlman D . 1970 . Microbial transformations of peptide antibiotics. V. Purification and properties of the actinomycin lactonase from Actinoplanes missouriensis . J. Biol. Chem. . 245 . 1289 - 95 . 4191854 . 6 .