Acrylyl-CoA reductase (NADH) explained

Acrylyl-CoA reductase (NADH)
Ec Number:	1.3.1.95

Acrylyl-CoA reductase (NADH) is an enzyme with systematic name propanoyl-CoA:NAD⁺ oxidoreductase.^{[1] [2]} This enzyme catalyses the following chemical reaction

propanoyl-CoA + NAD⁺

\rightleftharpoons acryloyl-CoA + NADH + H⁺

The reaction is catalysed in the opposite direction.

Notes and References

1. Hetzel M, Brock M, Selmer T, Pierik AJ, Golding BT, Buckel W . Acryloyl-CoA reductase from Clostridium propionicum. An enzyme complex of propionyl-CoA dehydrogenase and electron-transferring flavoprotein . European Journal of Biochemistry . 270 . 5 . 902–10 . March 2003 . 12603323 . 10.1046/j.1432-1033.2003.03450.x . free .
2. Kandasamy V, Vaidyanathan H, Djurdjevic I, Jayamani E, Ramachandran KB, Buckel W, Jayaraman G, Ramalingam S . Engineering Escherichia coli with acrylate pathway genes for propionic acid synthesis and its impact on mixed-acid fermentation . Applied Microbiology and Biotechnology . 97 . 3 . 1191–200 . February 2013 . 22810300 . 10.1007/s00253-012-4274-y .