Paraneoplastic acrokeratosis explained

Paraneoplastic acrokeratosis
Synonyms:	Acrokeratosis paraneoplastica of Bazex and Acrokeratosis neoplastica)^[1]

Paraneoplastic acrokeratosis, or Bazex syndrome is a cutaneous condition characterized by psoriasiform changes of hands, feet, ears, and nose, with involvement of the nails and periungual tissues being characteristic and indistinguishable from psoriatic nails. The condition is associated with carcinomas of the upper aerodigestive tract.^[2]

History

A case was first reported by Henri Gougerot and C. Grupper in 1922.^{[3] [4]} Andre Bazex described it as a paraneoplastic syndrome in 1965.^{[3] [5]}

See also

• List of cutaneous conditions
• Nail anatomy
• List of cutaneous conditions associated with increased risk of nonmelanoma skin cancer

Notes and References

1. Book: Rapini, Ronald P. . Bolognia, Jean L. . Jorizzo, Joseph L. . Dermatology: 2-Volume Set . Mosby . St. Louis . 2007 . 978-1-4160-2999-1 .
2. Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. .
3. Book: Chiesa-Fuxench . Zelma C. . Ramírez . Liliana . Sánchez . Néstor P. . Sánchez . Néstor P. . Atlas of Dermatology in Internal Medicine . 2011 . Springer Science & Business Media . New York . 978-1-4614-0687-7 . 66 . https://books.google.com/books?id=PACwY7Ms2F4C&pg=PA66 . en . Cutaneous manifestations of internal malignancy and paraneoplastic syndromes.
4. Gougerot, H. and Grupper, C., (1922). Dermatose érythémato-squameuse avec hyperkératose palmoplantaire, porectasies digitales et cancer de la langue latent. Paris Med, 43, pp.234-237
5. Bazex . A. . Griffiths . A. . Acrokeratosis paraneoplastica--a new cutaneous marker of malignancy . The British Journal of Dermatology . September 1980 . 103 . 3 . 301–306 . 10.1111/j.1365-2133.1980.tb07248.x . 7000146 . 0007-0963.