Acetylsalicylate deacetylase explained
| acetylsalicylate deacetylase |
| Ec Number: | 3.1.1.55 |
| Cas Number: | 87348-04-7 |
| Go Code: | 0047610 |
The enzyme acetylsalicylate deacetylase (EC 3.1.1.55) catalyzes the reaction
acetylsalicylate + H2O
salicylate + acetate
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is acetylsalicylate O-acetylhydrolase. Other names in common use include aspirin esterase, acetylsalicylic acid esterase, and aspirin hydrolase.
References
- Ali B, Kaur S . 1983 . Mammalian tissue acetylsalicylic acid esterase(s): identification, distribution and discrimination from other esterases . J. Pharmacol. Exp. Ther. . 226 . 589 - 94 . 6875867 . 2 .
- Kim DH, Yang YS, Jakoby WB . 1990 . Aspirin hydrolyzing esterases from rat liver cytosol . Biochem. Pharmacol. . 40 . 481 - 7 . 2383281 . 10.1016/0006-2952(90)90546-W . 3 .
- White KN, Hope DB . 1984 . Partial purification and characterization of a microsomal carboxylesterase specific for salicylate esters from guinea-pig liver . Biochim. Biophys. Acta . 785 . 138 - 47 . 6704404 . 3 . 10.1016/0167-4838(84)90138-9 .
