Acetyl-S-ACP:malonate ACP transferase explained
| Acetyl-S-ACP:malonate ACP transferase |
| Ec Number: | 2.3.1.187 |
Acetyl-S-ACP:malonate ACP transferase (acetyl-S-ACP:malonate ACP-SH transferase, acetyl-S-acyl-carrier protein:malonate acyl-carrier-protein-transferase, MdcA, MadA, ACP transferase, malonate/acetyl-CoA transferase, malonate:ACP transferase, acetyl-S-acyl carrier protein:malonate acyl carrier protein-SH transferase) is an enzyme with systematic name acetyl-(acyl-carrier-protein):malonate S-(acyl-carrier-protein)transferase.[1] [2] [3] [4] [5] This enzyme catalyses the following chemical reaction
malonyl-[acyl-carrier protein] +
acetateThis is the first step in the catalysis of malonate decarboxylation.
Notes and References
- Hilbi H, Dimroth P . Purification and characterization of a cytoplasmic enzyme component of the Na+-activated malonate decarboxylase system of Malonomonas rubra: acetyl-S-acyl carrier protein: malonate acyl carrier protein-SH transferase . Archives of Microbiology . 162 . 1-2 . 48–56 . 1994 . 18251085 . 10.1007/bf00264372 .
- Hoenke S, Schmid M, Dimroth P . Sequence of a gene cluster from Klebsiella pneumoniae encoding malonate decarboxylase and expression of the enzyme in Escherichia coli . European Journal of Biochemistry . 246 . 2 . 530–8 . June 1997 . 9208947 . 10.1111/j.1432-1033.1997.00530.x . free .
- Koo JH, Kim YS . Functional evaluation of the genes involved in malonate decarboxylation by Acinetobacter calcoaceticus . European Journal of Biochemistry . 266 . 2 . 683–90 . December 1999 . 10561613 . 10.1046/j.1432-1327.1999.00924.x . free .
- Chohnan S, Akagi K, Takamura Y . Functions of malonate decarboxylase subunits from Pseudomonas putida . Bioscience, Biotechnology, and Biochemistry . 67 . 1 . 214–7 . January 2003 . 12619701 . 10.1271/bbb.67.214 . free .
- Dimroth P, Hilbi H . Enzymic and genetic basis for bacterial growth on malonate . Molecular Microbiology . 25 . 1 . 3–10 . July 1997 . 11902724 . 10.1046/j.1365-2958.1997.4611824.x . free .
