Acetone azine explained

Acetone azine is the simplest ketazine. It is an intermediate in some hydrazine manufacturing processes.

Synthesis

See also: Peroxide process.

Acetone azine can be prepared from acetone and hydrazine:

2 (CH3)2CO + N2H4 → 2 H2O + [(CH<sub>3</sub>)<sub>2</sub>C=N]2

It can also be produced from acetone (2 eq.), ammonia (2 eq.) and hydrogen peroxide (1 eq.).[1] The first step is the formation of acetone imine, Me2C=NH; this is then oxidized by hydrogen peroxide through a complex mechanism to give 3,3-dimethyloxaziridine, which reacts with a further molecule of ammonia to produce acetone hydrazone. The hydrazone then condenses with a further molecule of acetone to produce the azine. The acetone azine product is distilled out of the reaction mixture as a 1:6 azeotrope with water.[2]

Reactions

Acetone azine can be used to prepare acetone hydrazone and .

Hydrazine can be produced through acid-catalysed hydrolysis of acetone azine:[3]

2 H2O + [(CH<sub>3</sub>)<sub>2</sub>C=N]2 → 2 (CH3)2CO + N2H4

Notes and References

  1. Jean-Pierre . Schirmann . Jean . Combroux . Serge Yvon . Delavarenne . . US . 3972878 . Method for preparing azines and hydrazones . 1976-08-03. .Jean-Pierre . Schirmann . Pierre . Tellier . Henri . Mathais . Francis . Weiss . . US . 3978049 . Process for the preparation of hydrazine compounds . 1976-08-31.
  2. Jean-Pierre . Schirmann . Jean . Combroux . Serge Y. . Delavarenne . . US . 4724133 . Preparation of a concentrated aqueous solution of hydrazine hydrate . 1988-02-09.
  3. .