Acefylline Explained

Acefylline (INN),^[1] also known as 7-theophyllineacetic acid, is a stimulant drug of the xanthine chemical class. It acts as an adenosine receptor antagonist. It is combined with diphenhydramine in the pharmaceutical preparation etanautine to help offset diphenhydramine induced drowsiness.^[2]

A silanol–mannuronic acid conjugate of acefylline, acefylline methylsilanol mannuronate (INCI; trade name Xantalgosil C) is marketed as a lipolytic phosphodiesterase inhibitor. It is used as an ingredient in cosmeceuticals for the treatment of cellulite and as a skin conditioner.^{[3] [4]}

See also

• 8-Chlorotheophylline
• Theophylline
• Caffeine

Notes and References

1. Web site: International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names (Rec. INN): List 21 . World Health Organization . 29 December 2016.
2. Biofarmaceutische en farmacokinetische aspecten van theofylline en acefylline . 1978 . Zuidema J . Thesis (doctoral)--Universiteit van Amsterdam . 2012-09-29 . https://web.archive.org/web/20161230000126/http://en.scientificcommons.org/33714038 . 2016-12-30 . dead .
3. Web site: Xantalgosil C® Datasheet . Biosil Technologies . PDF . Exsymol S.A.M. . 2005 . 2022-01-20.
4. Book: Winter, Ruth . 2009-10-20 . A Consumer's Dictionary of Cosmetic Ingredients . 7th . Harmony/Rodale . 42 . 9780307459862.