Norton Zinder Explained

Birth Name:Norton David Zinder
Birth Date:November 7, 1928
Birth Place:New York City, New York
Death Place:New York City, New York
Field:Microbiology
Work Institutions:Rockefeller University
Alma Mater:Columbia University (BA)
University of Wisconsin–Madison (PhD)
Doctoral Advisor:Joshua Lederberg
Doctoral Students:Harvey Lodish
Nina Fedoroff
Jef Boeke
Known For:Transduction
Virology
Prizes:Eli Lilly and Company-Elanco Research Award (1962)
NAS Award in Molecular Biology (1966)
AAAS Award for Scientific Freedom and Responsibility (1982)

Norton David Zinder (November 7, 1928 – February 3, 2012)[1] was an American biologist famous for his discovery of genetic transduction. Zinder was born in New York City, received his A.B. from Columbia University in 1947, Ph.D. from the University of Wisconsin–Madison in 1952, and became a member of the National Academy of Sciences in 1969. He led a lab at Rockefeller University until shortly before his death.[2]

In 1966 he was awarded the NAS Award in Molecular Biology from the National Academy of Sciences.[3]

Genetic transduction and RNA bacteriophage

Working as a graduate student with Joshua Lederberg,[4] [5] [6] Zinder discovered that a bacteriophage[7] can carry genes from one bacterium to another. Initial experiments were carried out using Salmonella. Zinder and Lederberg named this process of genetic exchange transduction.

Later, Zinder discovered the first bacteriophage that contained RNA as its genetic material. At that time, Harvey Lodish (now of the Massachusetts Institute of Technology and Whitehead Institute for Biomedical Research) worked in his lab.[8]

Norton Zinder died in 2012 of pneumonia after a long illness.[9]

Further reading

Notes and References

  1. Lodish . H. . Harvey Lodish. Fedoroff . N. . Nina Fedoroff. 10.1126/science.1220682 . Norton Zinder (1928-2012) . Science . 335 . 6074 . 1316 . 2012 . 22422973 . 2012Sci...335.1316L . 45292962 . free .
  2. Web site: Norton Zinder. 2021-06-24. Cold Spring Harbor Laboratory. en-US.
  3. Web site: NAS Award in Molecular Biology. National Academy of Sciences. 27 February 2011.
  4. Lederberg . J. . Zinder . N. . Norton Zinder. Concentration of biochemical mutants of bacteria with penicillin . Journal of the American Chemical Society . 70 . 12 . 4267–4268 . 1948 . 18105993 . 10.1021/ja01192a521.
  5. Lederberg . J. . Joshua Lederberg. Lederberg . E. M. . Zinder . N. D. . Norton Zinder. Lively . E. R. . Recombination analysis of bacterial heredity . Cold Spring Harbor Symposia on Quantitative Biology . 16 . 413–443 . 1951 . 14942753 . 10.1101/sqb.1951.016.01.030.
  6. Zinder . N. D. . Norton Zinder. Lederberg . J. . Joshua Lederberg. Genetic Exchange in Salmonella . Journal of Bacteriology . 64 . 5 . 679–699 . 1952 . 12999698 . 169409 . 10.1128/JB.64.5.679-699.1952.
  7. Kresge . N. . Simoni . R. D. . Hill . R. L. . The Molecular Genetics of Bacteriophage: The Work of Norton Zinder . The Journal of Biological Chemistry . 286 . 25 . e4–e5 . 2011 . 21830328 . 3121416 . 10.1074/jbc.o111.000244. free .
  8. Lodish . H. F. . Zinder . N. D. . Norton Zinder. 10.1126/science.152.3720.372 . Replication of the RNA of Bacteriophage f2 . Science . 152 . 3720 . 372–377 . 1966 . 17775172 . 1966Sci...152..372L . 32831602 .
  9. Nicolas Wade: Norton D. Zinder, Researcher in Molecular Biology, Dies at 83. In: The New York Times. February 7, 2012.