Zinc finger protein 516 explained

Zinc finger protein 516 is a protein that in humans is encoded by the ZNF516 gene.^[1]

Function

Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a zinc-finger protein, and belongs to the Krüppel C2H2-type zinc-finger protein family. It may be involved in transcriptional regulation.

Further reading

• Shaffer JR, Feingold E, Wang X, Lee M, Tcuenco K, Weeks DE, Weyant RJ, Crout R, McNeil DW, Marazita ML . GWAS of dental caries patterns in the permanent dentition . Journal of Dental Research . 92 . 1 . 38–44 . January 2013 . 23064961 . 3521449 . 10.1177/0022034512463579 .
• Shi Y, Sawada J, Sui G, Affar el B, Whetstine JR, Lan F, Ogawa H, Luke MP, Nakatani Y, Shi Y . Coordinated histone modifications mediated by a CtBP co-repressor complex . Nature . 422 . 6933 . 735–8 . April 2003 . 12700765 . 10.1038/nature01550 . 2670859 .
• Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N . Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain . DNA Research . 3 . 5 . 321–9, 341–54 . October 1996 . 9039502 . 10.1093/dnares/3.5.321 . free .
• Lee MG, Wynder C, Cooch N, Shiekhattar R . An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation . Nature . 437 . 7057 . 432–5 . September 2005 . 16079794 . 10.1038/nature04021 . 4396351 .
• Yashin AI, Wu D, Arbeev KG, Ukraintseva SV . Joint influence of small-effect genetic variants on human longevity . Aging . 2 . 9 . 612–20 . September 2010 . 20834067 . 2984609 . 10.18632/aging.100191 .
• O'Brien RP, Phelan PJ, Conroy J, O'Kelly P, Green A, Keogan M, O'Neill D, Jennings S, Traynor C, Casey J, McCormack M, Conroy R, Chubb A, Ennis S, Shields DC, Cavalleri GL, Conlon PJ . A genome-wide association study of recipient genotype and medium-term kidney allograft function . Clinical Transplantation . 27 . 3 . 379–87 . 2013 . 23432519 . 10.1111/ctr.12093 . 13087946 .

Notes and References

1. Web site: Entrez Gene: Zinc finger protein 516 .