| Ziguinchor | |
| Settlement Type: | Department |
| Mapsize: | 320px |
| Pushpin Label Position: | bottom |
| Pushpin Mapsize: | 300 |
| Subdivision Type: | Country |
| Subdivision Name: |  Senegal |
| Subdivision Type1: | Region |
| Subdivision Name1: | Ziguinchor Region |
| Subdivision Type2: | Capital |
| Subdivision Name2: | Ziguinchor |
| Area Total Km2: | 1153 |
| Population As Of: | 2023 census |
| Population Total: | 274,563 |
| Population Density Km2: | auto |
| Population Blank1 Title: | Ethnicities |
| Timezone: | GMT |
| Utc Offset: | +0 |
Ziguinchor Department is one of the 45 departments of Senegal, one of three located in the Ziguinchor Region in the south-west of the country.
The department has a single urban commune, that of Ziguinchor
The department is also divided administratively into two arrondissements, Niaguis Arrondissement and Nyassia Arrondissement which are in turn split into rural communities (Communautés rurales).