Zellballen Explained

A zellballen is a small nest of chromaffin cells or chief cells with pale eosinophilic staining. Zellballen are separated into groups by segmenting bands of fibrovascular stroma, and are surrounded by supporting sustentacular cells.[1] A zellballen pattern is diagnostic for paraganglioma or pheochromocytoma.[2]

Zellballen is German for "ball of cells".[3]

Notes and References

  1. Book: Robbins . Stanley L. . Cotran . Ramzi S. . Kumar . Vinay . Robbins and Cotran pathologic basis of disease . 2010 . Saunders/Elsevier . Philadelphia, PA . 9781437707922 . 1135 . 30 March 2017.
  2. Jashnani . KusumD . Patil . RoshniD . Balsarkar . DharmeshJ . 2013-10-01 . Loose cell clusters with vascular coats: Zellballen pattern of paraganglioma on cytology . Journal of Cytology . en . 30 . 4 . 278–279 . 10.4103/0970-9371.126670. 24648676 . 3945633 . free .
  3. Book: Sternberg's diagnostic surgical pathology . Mills . Stacey E. . Greenson . Joel K. . Hornick . Jason L. . Longacre . Teri A. . Reuter . Victor E. . 2015 . 9781451188752 . Sixth . Philadelphia . 890850970.

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