| Zamora River | |
| Subdivision Type1: | Country |
| Subdivision Name1: | Ecuador |
The Zamora River (Spanish: Río Zamora) is a tributary of the Santiago River located in the south-east of Ecuador. Historically, it was known to the Spanish as Yaya Mayu ("Father River"), from the river's name among a group of Shuar encountered nearby.
The sources of the Zamora River are in the Podocarpus National Park, specifically at the Nudo de Cajanuma. The river then descends towards the city of Loja. It crosses the provinces of Loja, Zamora-Chinchipe (wherein lies the city of Zamora) and Morona-Santiago, where it empties into the Santiago.
The Zamora is the dominant river in southeastern Ecuador, and has many tributaries, perhaps the source of its native name .
The most significant tributaries by province include: