ZP1 explained

Zona pellucida sperm-binding protein 1 is a protein that cross-links ZP2 and ZP3. Aberrant ZP1 results in sequestration of ZP3 in the cytoplasm, thereby preventing the formation of the zona pellucida around the oocyte.[1]

Notes and References

  1. Huang. Hua-Lin. Lv. Chao. Zhao. Ying-Chun. Li. Wen. He. Xue-Mei. Li. Ping. Sha. Ai-Guo. Tian. Xiao. Papasian. Christopher J.. Deng. Hong-Wen. Lu. Guang-Xiu. Xiao. Hong-Mei. Mutant ZP1 in Familial Infertility. New England Journal of Medicine. 370. 13. 2014. 1220–1226. 0028-4793. 10.1056/NEJMoa1308851. 24670168. 4076492.

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