Zinc finger protein 165 explained

Zinc finger protein 165 is a protein that in humans is encoded by the ZNF165 gene.^{[1] [2]}

Function

This gene encodes a member of the Kruppel family of zinc finger proteins. Members of this DNA-binding protein family act as transcriptional regulators. This gene is located within a cluster of zinc finger family members. The encoded protein may play a role in spermatogenesis.

Interactions

Zinc finger protein 165 has been shown to interact with Ewing sarcoma breakpoint region 1^[3] and DVL2.^[3]

See also

• Zinc finger

Further reading

• Lee PL, Gelbart T, West C, Adams M, Blackstone R, Beutler E . Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain. . Genomics . 43 . 2 . 191–201 . 1997 . 9244436 . 10.1006/geno.1997.4806 .
• Paoloni-Giacobino A, Kern I, Rumpler Y, Djlelati R, Morris MA, Dahoun SP . Familial t(6;21)(p21.1;p13) translocation associated with male-only sterility. . Clin. Genet. . 58 . 4 . 324–8 . 2001 . 11076058 . 10.1034/j.1399-0004.2000.580411.x . 19063057 .
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M . Towards a proteome-scale map of the human protein–protein interaction network. . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .

Notes and References

1. Tirosvoutis KN, Divane A, Jones M, Affara NA . Characterization of a novel zinc finger gene (ZNF165) mapping to 6p21 that is expressed specifically in testis . Genomics . 28 . 3 . 485–90 . Jan 1996 . 7490084 . 10.1006/geno.1995.1178 .
2. Web site: Entrez Gene: ZNF165 zinc finger protein 165.
3. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M . Towards a proteome-scale map of the human protein–protein interaction network. Huda Zoghbi . . 437 . 7062 . 1173–8 . Oct 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R. 4427026.