ZNF16 explained

Zinc finger protein 16 is a protein that in humans is encoded by the ZNF16 gene.^[1]

The protein encoded by this gene contains a C2H2 type of zinc finger, and thus may function as a transcription factor. This gene is located in a region close to ZNF7/KOX4, a gene also encoding a zinc finger protein, on chromosome 8. Two alternatively spliced variants, encoding the same protein, have been identified.^[1]

Further reading

• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Dreier B, Segal DJ, Barbas CF . Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains. . J. Mol. Biol. . 303 . 4 . 489–502 . 2000 . 11054286 . 10.1006/jmbi.2000.4133 .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Rousseau-Merck MF, Duro D, Berger R, Thiesen HJ . Chromosomal localization of two KOX zinc finger genes on chromosome bands 7q21-q22 . Ann. Genet. . 38 . 2 . 81–4 . 1995 . 7486829 .
• Thiesen HJ . Multiple genes encoding zinc finger domains are expressed in human T cells . New Biol. . 2 . 4 . 363–74 . 1991 . 2288909 .

Notes and References

1. Web site: Entrez Gene: ZNF16 zinc finger protein 16.