ZNF148 explained

Zinc finger protein 148 is a protein that in humans is encoded by the ZNF148 gene.^{[1] [2] [3]}

Interactions

ZNF148 has been shown to interact with PTRF^[4] and P53.^[5]

See also

• Zinc finger

Further reading

• Wang Y, Kobori JA, Hood L . The ht beta gene encodes a novel CACCC box-binding protein that regulates T-cell receptor gene expression . Molecular and Cellular Biology . 13 . 9 . 5691–701 . Sep 1993 . 8355710 . 360303 . 10.1128/mcb.13.9.5691.
• Merchant JL, Iyer GR, Taylor BR, Kitchen JR, Mortensen ER, Wang Z, Flintoft RJ, Michel JB, Bassel-Duby R . ZBP-89, a Krüppel-like zinc finger protein, inhibits epidermal growth factor induction of the gastrin promoter . Molecular and Cellular Biology . 16 . 12 . 6644–53 . Dec 1996 . 8943318 . 231666 . 10.1128/mcb.16.12.6644.
• Taniuchi T, Mortensen ER, Ferguson A, Greenson J, Merchant JL . Overexpression of ZBP-89, a zinc finger DNA binding protein, in gastric cancer . Biochemical and Biophysical Research Communications . 233 . 1 . 154–60 . Apr 1997 . 9144414 . 10.1006/bbrc.1997.6310 .
• Law DJ, Tarlé SA, Merchant JL . The human ZBP-89 homolog, located at chromosome 3q21, represses gastrin gene expression . Mammalian Genome . 9 . 2 . 165–7 . Feb 1998 . 9457682 . 10.1007/s003359900711 . 2027.42/42145 . 19151935 . free .
• Law GL, Itoh H, Law DJ, Mize GJ, Merchant JL, Morris DR . Transcription factor ZBP-89 regulates the activity of the ornithine decarboxylase promoter . The Journal of Biological Chemistry . 273 . 32 . 19955–64 . Aug 1998 . 9685330 . 10.1074/jbc.273.32.19955 . free .
• Ye S, Whatling C, Watkins H, Henney A . Human stromelysin gene promoter activity is modulated by transcription factor ZBP-89 . FEBS Letters . 450 . 3 . 268–72 . May 1999 . 10359087 . 10.1016/S0014-5793(99)00509-8 . 1858952 . free . 1999FEBSL.450..268Y .
• Hasegawa T, Takeuchi A, Miyaishi O, Xiao H, Mao J, Isobe K . PTRF (polymerase I and transcript-release factor) is tissue-specific and interacts with the BFCOL1 (binding factor of a type-I collagen promoter) zinc-finger transcription factor which binds to the two mouse type-I collagen gene promoters . The Biochemical Journal . 347 Pt 1 . Pt 1 . 55–9 . Apr 2000 . 10727401 . 1220930 . 10.1042/0264-6021:3470055 .
• Bai L, Merchant JL . Transcription factor ZBP-89 cooperates with histone acetyltransferase p300 during butyrate activation of p21waf1 transcription in human cells . The Journal of Biological Chemistry . 275 . 39 . 30725–33 . Sep 2000 . 10899165 . 10.1074/jbc.M004249200 . free .
• Bai L, Merchant JL . ZBP-89 promotes growth arrest through stabilization of p53 . Molecular and Cellular Biology . 21 . 14 . 4670–83 . Jul 2001 . 11416144 . 87140 . 10.1128/MCB.21.14.4670-4683.2001 .
• Park H, Shelley CS, Arnaout MA . The zinc finger transcription factor ZBP-89 is a repressor of the human beta 2-integrin CD11b gene . Blood . 101 . 3 . 894–902 . Feb 2003 . 12393719 . 10.1182/blood-2002-03-0680 . free .
• Chen GG, Merchant JL, Lai PB, Ho RL, Hu X, Okada M, Huang SF, Chui AK, Law DJ, Li YG, Lau WY, Li AK . Mutation of p53 in recurrent hepatocellular carcinoma and its association with the expression of ZBP-89 . The American Journal of Pathology . 162 . 6 . 1823–9 . Jun 2003 . 12759240 . 1868140 . 10.1016/S0002-9440(10)64317-9 .
• Wu Y, Diab I, Zhang X, Izmailova ES, Zehner ZE . Stat3 enhances vimentin gene expression by binding to the antisilencer element and interacting with the repressor protein, ZBP-89 . Oncogene . 23 . 1 . 168–78 . Jan 2004 . 14712222 . 10.1038/sj.onc.1207003 . free .
• Bai L, Yoon SO, King PD, Merchant JL . ZBP-89-induced apoptosis is p53-independent and requires JNK . Cell Death and Differentiation . 11 . 6 . 663–73 . Jun 2004 . 14963412 . 10.1038/sj.cdd.4401393 . free .
• Samuelsson L, Stiller C, Friberg C, Nilsson C, Inerot A, Wahlström J . Association analysis of cystatin A and zinc finger protein 148, two genes located at the psoriasis susceptibility locus PSORS5 . The Journal of Investigative Dermatology . 122 . 6 . 1399–400 . Jun 2004 . 15175029 . 10.1046/j.0022-202X.2004.12604.x . free .
• Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP . Large-scale characterization of HeLa cell nuclear phosphoproteins . Proceedings of the National Academy of Sciences of the United States of America . 101 . 33 . 12130–5 . Aug 2004 . 15302935 . 514446 . 10.1073/pnas.0404720101 . 2004PNAS..10112130B . free .

Notes and References

1. Tommerup N, Vissing H . Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders . Genomics . 27 . 2 . 259–64 . May 1995 . 7557990 . 10.1006/geno.1995.1040 .
2. Antona V, Cammarata G, De Gregorio L, Dragani TA, Giallongo A, Feo S . The gene encoding the transcriptional repressor BERF-1 maps to a region of conserved synteny on mouse chromosome 16 and human chromosome 3 and a related pseudogene maps to mouse chromosome 8 . Cytogenetics and Cell Genetics . 83 . 1–2 . 90–2 . March 1999 . 9925940 . 10.1159/000015138 . 2024-07-25 . 27825125 .
3. Web site: Entrez Gene: ZNF148 zinc finger protein 148.
4. Hasegawa T, Takeuchi A, Miyaishi O, Xiao H, Mao J, Isobe K . PTRF (polymerase I and transcript-release factor) is tissue-specific and interacts with the BFCOL1 (binding factor of a type-I collagen promoter) zinc-finger transcription factor which binds to the two mouse type-I collagen gene promoters . The Biochemical Journal . 347 Pt 1 . Pt 1 . 55–9 . Apr 2000 . 10727401 . 1220930 . 10.1042/0264-6021:3470055 .
5. Bai L, Merchant JL . ZBP-89 promotes growth arrest through stabilization of p53 . Molecular and Cellular Biology . 21 . 14 . 4670–83 . Jul 2001 . 11416144 . 87140 . 10.1128/MCB.21.14.4670-4683.2001 .