ZFP91 explained

Zinc finger protein 91 homolog is a protein that in humans is encoded by the ZFP91 gene.^[1]

The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2 type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. In addition to the monocistronic transcript originating from this locus, a co-transcribed variant composed of ZFP91 and CNTF sequence has been identified. The monocistronic and co-transcribed variants encode distinct isoforms. The co-transcription of ZFP91 and CNTF has also been observed in mouse.^[2]

Further reading

• Iuchi S . Three classes of C2H2 zinc finger proteins. . Cell. Mol. Life Sci. . 58 . 4 . 625–35 . 2001 . 11361095 . 10.1007/PL00000885 . 6522993 . 11146492 .
• Grottke C, Mantwill K, Dietel M, etal . Identification of differentially expressed genes in human melanoma cells with acquired resistance to various antineoplastic drugs. . Int. J. Cancer . 88 . 4 . 535–46 . 2000 . 11058868 . 10.1002/1097-0215(20001115)88:4<535::AID-IJC4>3.0.CO;2-V . 24030621 .
• Yu Y, Zhang C, Zhou G, etal . Gene Expression Profiling in Human Fetal Liver and Identification of Tissue- and Developmental-Stage-Specific Genes through Compiled Expression Profiles and Efficient Cloning of Full-Length cDNAs . Genome Res. . 11 . 8 . 1392–403 . 2001 . 11483580 . 10.1101/gr.175501 . 311073 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Obuse C, Yang H, Nozaki N, etal . Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase . Genes Cells . 9 . 2 . 105–20 . 2004 . 15009096 . 10.1111/j.1365-2443.2004.00705.x . 21813024 . free .
• Beausoleil SA, Jedrychowski M, Schwartz D, etal . Large-scale characterization of HeLa cell nuclear phosphoproteins . Proc. Natl. Acad. Sci. U.S.A. . 101 . 33 . 12130–5 . 2004 . 15302935 . 10.1073/pnas.0404720101 . 514446 . 2004PNAS..10112130B . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Tompkins V, Hagen J, Zediak VP, Quelle DE . Identification of novel ARF binding proteins by two-hybrid screening . Cell Cycle . 5 . 6 . 641–6 . 2006 . 16582619 . 10.4161/cc.5.6.2560. free .
• Olsen JV, Blagoev B, Gnad F, etal . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks . Cell . 127 . 3 . 635–48 . 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . 7827573 . free .

Notes and References

1. Unoki M, Okutsu J, Nakamura Y . Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia . Int J Oncol . 22 . 6 . 1217–23 . May 2003 . 12738986 . 10.3892/ijo.22.6.1217.
2. Web site: Entrez Gene: ZFP91 zinc finger protein 91 homolog (mouse).