ZDHHC8 explained

ZDHHC8 is a putative palmitoyltransferase enzyme containing a DHHC domain that in humans is encoded by the ZDHHC8 gene.^{[1] [2] [3]}

Further reading

• Dunham I, Shimizu N, Roe BA, etal . The DNA sequence of human chromosome 22. . Nature . 402 . 6761 . 489–95 . 1999 . 10591208 . 10.1038/990031 . 1999Natur.402..489D . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Collins JE, Wright CL, Edwards CA, etal . A genome annotation-driven approach to cloning the human ORFeome. . Genome Biol. . 5 . 10 . R84 . 2005 . 15461802 . 10.1186/gb-2004-5-10-r84 . 545604 . free .
• Chen WY, Shi YY, Zheng YL, etal . Case-control study and transmission disequilibrium test provide consistent evidence for association between schizophrenia and genetic variation in the 22q11 gene ZDHHC8. . Hum. Mol. Genet. . 13 . 23 . 2991–5 . 2005 . 15489219 . 10.1093/hmg/ddh322 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Saito S, Ikeda M, Iwata N, etal . No association was found between a functional SNP in ZDHHC8 and schizophrenia in a Japanese case-control population. . Neurosci. Lett. . 374 . 1 . 21–4 . 2005 . 15631889 . 10.1016/j.neulet.2004.10.015 . 24312967 .
• Glaser B, Schumacher J, Williams HJ, etal . No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples. . Biol. Psychiatry . 58 . 1 . 78–80 . 2005 . 15992527 . 10.1016/j.biopsych.2005.03.017 . 20264569 .
• Otani K, Ujike H, Tanaka Y, etal . The ZDHHC8 gene did not associate with bipolar disorder or schizophrenia. . Neurosci. Lett. . 390 . 3 . 166–70 . 2006 . 16150541 . 10.1016/j.neulet.2005.08.019 . 26919027 .
• Demily C, Legallic S, Bou J, etal . ZDHHC8 single nucleotide polymorphism rs175174 is not associated with psychiatric features of the 22q11 deletion syndrome or schizophrenia. . Psychiatr. Genet. . 17 . 5 . 311–2 . 2007 . 17728672 . 10.1097/YPG.0b013e328133f369 .

Notes and References

1. Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O . Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro . DNA Res . 6 . 5 . 337–45 . Jan 2000 . 10574462 . 10.1093/dnares/6.5.337 . free .
2. Mukai J, Liu H, Burt RA, Swor DE, Lai WS, Karayiorgou M, Gogos JA . Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia . Nat Genet . 36 . 7 . 725–31 . Jun 2004 . 15184899 . 10.1038/ng1375 . free .
3. Web site: Entrez Gene: ZDHHC8 zinc finger, DHHC-type containing 8.