ZBTB7B explained

Zinc finger and BTB domain-containing protein 7B is a protein that in humans is encoded by the ZBTB7B gene.^{[1] [2] [3]} ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes (e.g. COL1A1; MIM 120150) and has a role in development.[supplied by OMIM]

See also

• Zbtb7

Further reading

• Heegaard AM . Functional characterization of the human biglycan 5'-flanking DNA and binding of the transcription factor c-Krox . J. Bone Miner. Res. . 12 . 12 . 2050–60 . 1998 . 9421237 . 10.1359/jbmr.1997.12.12.2050 . vanc. Gehron Robey P . Vogel W . 3 . Just . Walter . Widom . Russell L. . Schøller . Jørgen . Fisher . Larry W. . Young . Marian F. . 29523309 .
• Ghayor C . Regulation of human COL2A1 gene expression in chondrocytes. Identification of C-Krox-responsive elements and modulation by phenotype alteration . J. Biol. Chem. . 275 . 35 . 27421–38 . 2000 . 10856292 . 10.1074/jbc.M002139200 . vanc. Herrouin JF . Chadjichristos C . 3 . Ala-Kokko . L . Takigawa . M . Pujol . JP . Galéra . P . free .
• Widom RL . The hcKrox gene family regulates multiple extracellular matrix genes . Matrix Biol. . 20 . 7 . 451–62 . 2002 . 11691585 . 10.1016/S0945-053X(01)00167-6 . vanc. Lee JY . Joseph C . 3 . Gordon-Froome . Ingrid . Korn . Joseph H. .
• Strausberg RL . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . vanc. Feingold EA . Grouse LH . 3 . Derge . JG . Klausner . RD . Collins . FS . Wagner . L . Shenmen . CM . Schuler . GD . 2002PNAS...9916899M . free .
• Gerhard DS . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . vanc. Wagner L . Feingold EA . 3 . Shenmen . CM . Grouse . LH . Schuler . G . Klein . SL . Old . S . Rasooly . R .
• Rual JF . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . vanc. Venkatesan K . Hao T . 3 . Hirozane-Kishikawa . Tomoko . Dricot . Amélie . Li . Ning . Berriz . Gabriel F. . Gibbons . Francis D. . Dreze . Matija . 2005Natur.437.1173R . 4427026 .
• Gregory SG . The DNA sequence and biological annotation of human chromosome 1 . Nature . 441 . 7091 . 315–21 . 2006 . 16710414 . 10.1038/nature04727 . vanc. Barlow KF . McLay KE . 3 . Kaul . R. . Swarbreck . D. . Dunham . A. . Scott . C. E. . Howe . K. L. . Woodfine . K. . 2006Natur.441..315G . free .
• Kypriotou M . Human collagen Krox up-regulates type I collagen expression in normal and scleroderma fibroblasts through interaction with Sp1 and Sp3 transcription factors . J. Biol. Chem. . 282 . 44 . 32000–14 . 2007 . 17698844 . 10.1074/jbc.M705197200 . vanc. Beauchef G . Chadjichristos C . 3 . Widom . R. . Renard . E. . Jimenez . S. A. . Korn . J. . Maquart . F.-X. . Oddos . T. . free .

Notes and References

1. Widom RL, Culic I, Lee JY, Korn JH . Cloning and characterization of hcKrox, a transcriptional regulator of extracellular matrix gene expression . Gene . 198 . 1–2 . 407–20 . Dec 1997 . 9370309 . 10.1016/S0378-1119(97)00360-0 . free .
2. Galera P, Musso M, Ducy P, Karsenty G . c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin . Proc Natl Acad Sci U S A . 91 . 20 . 9372–6 . Oct 1994 . 7937772 . 44814 . 10.1073/pnas.91.20.9372 . 1994PNAS...91.9372G . free .
3. Web site: Entrez Gene: ZBTB7B zinc finger and BTB domain containing 7B.