Z-Cote Explained

Z-Cote is a commercial zinc oxide line[1] manufactured and owned by BASF.[2] Due to Z-Cote's photo-protective properties it is commonly used in personal care products and sunscreens. It is available in nano, non-nano, coated and uncoated forms.[3] Z-Cote is a derivative of zinc oxide which is Generally Recognized As Safe and Effective (GRASE) by the FDA as a nutrient,[4] cosmetic colour additive,[5] [6] skin protection active ingredient[7] and other OTC products.[8] Manufactured zinc oxide, such as Z-Cote, is only recognised as GRASE by the FDA when it is compliant with the Good manufacturing practice (GMP) standard. The original Sunsmart and Submicro Encapsulation Technologies Z-Cote patent filed in 1991 for UV skin protection expired in 2015.[9]

History

Z-Cote was acquired from SunSmart in 1999 by BASF.[10] [11] It has been used in sunscreen formulations since at least 1993 in microfine form.[12] The initial 1991 Z-Cote patent placed emphasis on broad-spectrum protection, especially UVA. Only in 1993 did the FDA approve an alternative petrochemical sunscreen ingredient, avobenzone, that also provided protection against UVA.[13] [14]

Environmental impact

Plants

Z-Cote was studied to evaluate hypothetical agricultural impacts if it were to contaminate irrigated water. In the study it was found that Z-Cote had a negligible impact on bean (Phaseolus vulgaris) pod production and increased root length and the concentration of more nutritional elements.[15]

Reef

Zinc oxide is compliant with Hawaii Act 104 banning non-reef safe petrochemicals.[16]

Zinc oxide producers

Notes and References

  1. Web site: Zinc Oxide GCIMagazine.com . 2022-10-31 . dir.gcimagazine.com.
  2. Yin . Hong . Coleman . Victoria A. . Casey . Phil S. . Angel . Brad . Catchpoole . Heather J. . Waddington . Lynne . McCall . Maxine J. . 2015-02-17 . A comparative study of the physical and chemical properties of nano-sized ZnO particles from multiple batches of three commercial products . Journal of Nanoparticle Research . en . 17 . 2 . 96 . 10.1007/s11051-014-2851-y . 95188994 . 1572-896X.
  3. Web site: 2019 . Z-COTE® Zinc Oxide - Formulation Concepts . Care Creations - BASF US . . Florham Park, NJ.
  4. Web site: CFR - Code of Federal Regulations Title 21 - Subchapter B . 2022-11-16 . www.accessdata.fda.gov.
  5. Web site: CFR - Code of Federal Regulations Title 21 - Subchapter A . 2022-11-16 . www.accessdata.fda.gov.
  6. Web site: CFR - Code of Federal Regulations Title 21 - Subchapter A . 2022-11-16 . www.accessdata.fda.gov.
  7. Web site: CFR - Code of Federal Regulations Title 21 - Subchapter D . 2022-11-16 . www.accessdata.fda.gov.
  8. Web site: Federal Register :: Request Access . 2022-11-16 . unblock.federalregister.gov.
  9. 5733531 . Composite UV sunblock compositions . US . 1998-03-31 . Sunsmart Inc. . Submicro Encapsulation Technologies Inc. . Mitchnick . Mark A. . Gwozdz . Garry T. . Micale . Fortunato J..
  10. Web site: 13 December 1999 . BASF Acquires Z-COTE Micro Zinc Oxide Ingredient From SunSmart . Pink Sheet - Pharma Intelligence . The Rose Sheet.
  11. Web site: SEC . Basf Akteingesellschaft /adr/ Form for initial registration of a class of securities of foreign private issuers pursuant to section 12(b) 20FR12B . 2022-11-01 . SEC.report . en.
  12. 5417961. Sunscreen compositions. US. 1995-05-23. Colgate-Palmolive Company. Nearn. Malcolm R.. Redshaw. Sandra J.. Burgess. Graham.
  13. Web site: May 21, 1999 . 27666 Federal Register / Vol. 64, No. 98 / Friday, May 21, 1999 /Rules and Regulations . GovInfo U.S. Government Publishing Office.
  14. Beasley . Donathan G. . Meyer . Thomas A. . 2010-12-01 . Characterization of the UVA protection provided by avobenzone, zinc oxide, and titanium dioxide in broad-spectrum sunscreen products . American Journal of Clinical Dermatology . 11 . 6 . 413–421 . 10.2165/11537050-000000000-00000 . 1179-1888 . 20806994. 5984535 .
  15. Medina-Velo . Illya A. . Barrios . Ana C. . Zuverza-Mena . Nubia . Hernandez-Viezcas . Jose A. . Chang . Chong Hyun . Ji . Zhaoxia . Zink . Jeffrey I. . Peralta-Videa . Jose R. . Gardea-Torresdey . Jorge L. . 2017-06-15 . Comparison of the effects of commercial coated and uncoated ZnO nanomaterials and Zn compounds in kidney bean (Phaseolus vulgaris) plants . Journal of Hazardous Materials . en . 332 . 214–222 . 10.1016/j.jhazmat.2017.03.008 . 28359954 . 0304-3894. free .
  16. Web site: IGE . GOVERNOR DAVID Y. . CHAR . M.D. ELIZABETH A. . 2021-02-17 . Testimony COMMENTING on SB0132 RELATING TO WATER POLLUTION SENATOR MIKE GABBARD, CHAIR SENATOR CLARENCE K. NISHIHARA, VICE CHAIR SENATE COMMITTEE ON AGRICULTURE & ENVIRONMENT .

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