| Yuriy Mikhaylus | |
| Fullname: | Yuriy Ivanovich Mikhaylus |
| Birth Date: | 17 June 1964 |
| Birth Place: | Russian SFSR |
| Position: | Midfielder |
| Years1: | 1992–1993 |
| Years2: | 1993–1994 |
| Clubs1: | SC Tavriya Simferopol |
| Clubs2: | FC Surozh Sudak |
| Caps1: | 2 |
| Caps2: | 32 |
| Goals1: | 0 |
| Goals2: | 5 |
Yuriy Ivanovich Mikhaylus (Russian: Юрий Иванович Михайлус; born 17 June 1964) is a former Soviet and Ukrainian footballer, the champion of Ukraine with SC Tavriya Simferopol.