| Yousef Sheikh Al-Eshra | |
| Birth Date: | 15 January 1979 |
| Birth Place: | Syria |
| Height: | 1.78 m |
| Position: | Defender |
| Years1: | 2003–2004 |
| Years2: | 2004–2010 |
| Years3: | 2010–2015 |
| Nationalteam1: | Syria |
Yousef Sheikh Al-Eshra (Arabic: يوسف شيخ العشرة; born 15 January 1979) is a Syrian footballer who played for Syria national football team.