| Yevgeni Nikishin | |
| Fullname: | Yevgeni Prokofyevich Nikishin |
| Birth Date: | 21 May 1904 |
| Birth Place: | Moscow, Russian Empire |
| Death Place: | Moscow, Soviet Union |
| Position: | Midfielder |
| Youthclubs1: | OLLS Moscow |
| Years1: | 1921–1938 |
| Manageryears1: | 1943–1944 |
| Managerclubs1: | FC CSKA Moscow |
| Manageryears2: | 1944–1947 |
| Managerclubs2: | FC CSKA Moscow (assistant) |
Yevgeni Prokofyevich Nikishin (Russian: Евгений Прокофьевич Никишин; 21 May 1904 in Moscow – 25 March 1965 in Moscow) was a Soviet Russian football player and coach.