| Official Name: | Yeskino |
| Native Name: | Ескино |
| Settlement Type: | Village |
| Pushpin Map: | Russia Vologda Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Name1: | Vologda Oblast |
| Subdivision Name3: | Syamzhensky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 60.0333°N 65°W[1] |
Yeskino (Russian: Ескино) is a rural locality (a village) in Korobitsynskoye Rural Settlement, Syamzhensky District, Vologda Oblast, Russia. The population was 18 as of 2002.[2]
Yeskino is located 38 km northeast of Syamzha (the district's administrative centre) by road. Borisovskaya is the nearest rural locality.[3]