| Yesaya Desnam | |
| Fullname: | Yesaya Nickhanor Desnam |
| Birth Date: | 1985 6, df=y |
| Birth Place: | Merauke, Papua, Indonesia |
| Height: | 1.84 m |
| Position: | Centre Back, Left Back |
| Years1: | 2005–2006 |
| Caps1: | 20 |
| Goals1: | 0 |
| Years2: | 2006–2015 |
| Caps2: | 180 |
| Goals2: | 5 |
| Years3: | 2015–2016 |
| Caps3: | 19 |
| Goals3: | 3 |
| Years4: | 2016 |
| Caps4: | 10 |
| Goals4: | 0 |
| Years5: | 2017 |
| Clubs5: | Persiwa Wamena |
| Caps5: | 12 |
| Goals5: | 0 |
| Totalcaps: | 251 |
| Totalgoals: | 8 |
| Nationalyears1: | 2010 |
| Nationalteam1: | Indonesia |
| Nationalcaps1: | 1 |
| Nationalgoals1: | 0 |
Yesaya Nickhanor Desnam[1] or Yesaya Desnam[2] is an Indonesian former footballer.His natural position is defender. He is the first Asmat to play for Indonesia. He was in the squad for 2010 AFF Championship.