| Yesagyo | |
| Native Name: | ရေစကြိုမြို့ |
| Settlement Type: | Town |
| Pushpin Map: | Burma |
| Pushpin Label Position: | right |
| Pushpin Map Caption: | Location in Burma |
| Subdivision Type: | Country |
| Subdivision Name: |  Myanmar |
| Subdivision Type1: | Region |
| Subdivision Type2: | District |
| Subdivision Name2: | Pakokku District |
| Subdivision Type3: | Township |
| Subdivision Name3: | Yesagyo Township |
| Population As Of: | 2014 Cenus |
| Population Total: | 23,603 |
| Timezone: | MST |
| Utc Offset: | +6.30 |
| Coordinates: | 21.6333°N 95.2414°W |
Yesagyo (my|ရေစကြိုမြို့) is a town in the Magway Division in Myanmar. It is situated on the Chindwin River, near the site where it flows into Irrawaddy River. It is the principal town and administrative seat of Yesagyo Township.Yesagyo is a second biggest city of Pakokku District.