Ethinylestradiol/drospirenone explained

Ethinylestradiol/drospirenone (EE/DRSP), sold under the brand name Yasmin among others, is a combination of ethinylestradiol (EE), an estrogen, and drospirenone (DRSP), a progestin, antimineralocorticoid, and antiandrogen, which is used as a birth control pill to prevent pregnancy in women.[1] [2] [3] [4] [5] It is also indicated for the treatment of moderate acne, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), and dysmenorrhea (painful menstruation) in women. The medication is taken by mouth and contains 30 μg EE and 3 mg DRSP per tablet (brand names Yasmin, others) or 20 μg EE and 3 mg DRSP per tablet (brand names Yaz, Yasminelle, Nikki, others). A formulation with levomefolic acid (vitamin B9) has also been marketed (brand names Beyaz, Safyral, others), with similar indications.[6] [7] EE/DRSP is marketed widely throughout the world.[8]

In 2021, it was the 152nd most commonly prescribed medication in the United States, with more than 3million prescriptions.[9] [10]

See also

Notes and References

  1. Web site: Ethinylestradiol/Drospirenone . AdisInsight . Springer Nature Switzerland AG .
  2. Web site: Drospirenone/Ethinylestradiol low-dose - Bayer HealthCare Pharmaceuticals . AdisInsight . Springer Nature Switzerland AG .
  3. Web site: Bayer HealthCare Pharmaceuticals Inc. . U.S. Food and Drug Administration . Highlights of Prescribing Information: Yasmin .
  4. Web site: Bayer HealthCare Pharmaceuticals Inc . U.S. Food and Drug Administration . Highlights of Prescribing Information: Yaz . 31 October 2017.
  5. Keam SJ, Wagstaff AJ . Ethinylestradiol/drospirenone: a review of its use as an oral contraceptive . Treatments in Endocrinology . 2 . 1 . 49–70 . 2003 . 15871554 . 10.2165/00024677-200302010-00005 . 209144694 .
  6. Web site: Ethinylestradiol/Drospirenone/Folic acid . AdisInsight . Springer Nature Switzerland AG .
  7. Web site: Bayer HealthCare Pharmaceuticals Inc. . Highlights of Prescribing Information: Beyaz . U.S. Food and Drug Administration .
  8. Web site: Drospirenone Uses, Side Effects & Warnings . Drugs.com .
  9. Web site: The Top 300 of 2021 . ClinCalc . 14 January 2024 . 15 January 2024 . https://web.archive.org/web/20240115223848/https://clincalc.com/DrugStats/Top300Drugs.aspx . live .
  10. Web site: Drospirenone; Ethinyl Estradiol - Drug Usage Statistics . ClinCalc . 14 January 2024 .

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