Yaequinolone J1 Explained

Yaequinolone J1 is an antibiotic made by Penicillium.[1]

Total syntheses of yaequinolone J1

An asymmetric total synthesis of yaequinolone J1 has been published in 2018 by V. Vece, S. Jakkepally and S. Hanessian.[2] In 2020, a five-step synthesis of yaequinolone J1 was reported.[3]

Notes and References

  1. Yaequinolones J1 and J2, novel insecticidal antibiotics from Penicillium sp. FKI-2140. 16321026 . 10.1021/ol052458h . 7. Org Lett. 5701–4 . Uchida . R . Imasato . R . Shiomi . K . Tomoda . H . Omura . S. 2005 . 25 .
  2. Total Synthesis and Absolute Stereochemical Assignment of the Insecticidal Metabolites Yaequinolones J1 and J2. 10.1021/acs.orglett.8b01701 . Vece . V . Jakkepally . S . Hanessian . S . 2018. Org. Lett.. 20. 14. 4277–4280. 29975546 . 49710214 .
  3. Five-Step Synthesis of Yaequinolones J1 and J2. 10.1021/acs.orglett.9b04455 . Schwan. J . Kleoff. M . Heretsch . P . Christmann. M . 2020. Org. Lett.. 22. 2. 475–479. 31909626 .

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