Xinnian Dong Explained

Xinnian Dong
Native Name:董欣年
Native Name Lang:zh
Birth Place:Wuhan, Hubei, China
Nationality:American
Fields:Molecular biology
Plant physiology
Workplaces:Duke University
Alma Mater:Wuhan University
Northwestern University
Harvard University
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Spouse:Xiao-Fan Wang

Xinnian Dong (; born 1959) is a Chinese-American biologist who is the current Arts and Sciences Professor of Biology in the Trinity College of Arts and Sciences, Duke University, United States. She is a member of the US National Academy of Sciences.[1] [2]

Biography

Dong was born in Wuhan, Hubei, China in 1959, to Dong Fureng, a Chinese-American economist, and Liu Ainian, a Chinese-American ophthalmologist.[3] After resuming the college entrance examination, Dong was accepted to Wuhan University, where she graduated in 1982. After college, she attended the China-United States Biochemistry Examination and Application (CUSBEA) and was sent abroad to study at the expense of the Chinese government, along with her husband, Xiao-Fan Wang. In 1983, she pursued advanced studies in the United States, earning her doctorate from Northwestern University in 1988. Dong did post-doctoral research at Harvard University from 1988 to 1991. Dong joined the faculty of Duke University in 1992 and established the Dong Lab.

Since 1992, Dr. Dong and the Dong Lab has studied plant-microbe interactions with an emphasis on systemic acquired resistance (SAR)[4] The Lab's early work involved the identification of key components in SAR, including NPR1.[5] [6] [7] [8] More recently, the Lab made discoveries which provided new insights into the relationship between pathogen-induced cellular redox changes and induced immune responses in plants[9] and the role of ER-resident genes in the modification and secretion of antimicrobial proteins.[10] Most recently, the Lab has conducted genomic studies, leading to the discovery of new components in R gene-mediated resistance against downy mildew (Hyaloperonospora parasitica).[11] They also currently investigate links between chromatin stability and plant defense.[12]

Personal life

She became a naturalized US citizen in 1998. Dong was married to Xiao-Fan Wang, a Chinese American oncologist.[13] [14]

Awards and honors

Notes and References

  1. News: XINNIAN DONG . 12 October 2018 . asm.org . 2018 .
  2. News: Profile of Xinnian Dong . 12 October 2018 . pnas.org . 2018 . 12 October 2018 . https://web.archive.org/web/20181012054158/http://www.pnas.org/content/112/36/11144 . dead .
  3. News: http://business.sohu.com/20040812/n221501507.shtml . zh:董欣年：爸爸您好好休息吧（图） . Sohu . 2004-08-12 . zh.
  4. Web site: Dong Lab Plant Immunity and Microbe Interactions. 2020-07-12. en-US.
  5. Tada. Y.. Spoel. S. H.. Pajerowska-Mukhtar. K.. Mou. Z.. Song. J.. Wang. C.. Zuo. J.. Dong. X.. 2008-08-15. Plant Immunity Requires Conformational Charges of NPR1 via S-Nitrosylation and Thioredoxins. Science. en. 321. 5891. 952–956. 10.1126/science.1156970. 0036-8075. 3833675. 18635760. 2008Sci...321..952T .
  6. Spoel. Steven H.. Mou. Zhonglin. Tada. Yasuomi. Spivey. Natalie W.. Genschik. Pascal. Dong. Xinnian. May 2009. Proteasome-Mediated Turnover of the Transcription Coactivator NPR1 Plays Dual Roles in Regulating Plant Immunity. Cell. en. 137. 5. 860–872. 10.1016/j.cell.2009.03.038. 19490895. 2704463.
  7. Saleh. Abdelaty. Withers. John. Mohan. Rajinikanth. Marqués. Jorge. Gu. Yangnan. Yan. Shunping. Zavaliev. Raul. Nomoto. Mika. Tada. Yasuomi. Dong. Xinnian. August 2015. Posttranslational Modifications of the Master Transcriptional Regulator NPR1 Enable Dynamic but Tight Control of Plant Immune Responses. Cell Host & Microbe. en. 18. 2. 169–182. 10.1016/j.chom.2015.07.005. 4537515. 26269953.
  8. Withers. John. Dong. Xinnian. 2016-08-11. Zipfel. Cyril. Posttranslational Modifications of NPR1: A Single Protein Playing Multiple Roles in Plant Immunity and Physiology. PLOS Pathogens. en. 12. 8. e1005707. 10.1371/journal.ppat.1005707. 1553-7374. 4981451. 27513560 . free .
  9. Tada. Y.. Spoel. S. H.. Pajerowska-Mukhtar. K.. Mou. Z.. Song. J.. Wang. C.. Zuo. J.. Dong. X.. 2008-08-15. Plant Immunity Requires Conformational Charges of NPR1 via S-Nitrosylation and Thioredoxins. Science. en. 321. 5891. 952–956. 10.1126/science.1156970. 0036-8075. 3833675. 18635760. 2008Sci...321..952T .
  10. Saleh. Abdelaty. Withers. John. Mohan. Rajinikanth. Marqués. Jorge. Gu. Yangnan. Yan. Shunping. Zavaliev. Raul. Nomoto. Mika. Tada. Yasuomi. Dong. Xinnian. August 2015. Posttranslational Modifications of the Master Transcriptional Regulator NPR1 Enable Dynamic but Tight Control of Plant Immune Responses. Cell Host & Microbe. en. 18. 2. 169–182. 10.1016/j.chom.2015.07.005. 4537515. 26269953.
  11. Clarke. Joseph D.. Liu. Yidong. Klessig. Daniel F.. Dong. Xinnian. 1998-04-01. Uncoupling PR Gene Expression from NPR1 and Bacterial Resistance: Characterization of the Dominant Arabidopsis cpr6-1 Mutant. The Plant Cell. en. 10. 4. 557–569. 10.1105/tpc.10.4.557. 1040-4651. 144011. 9548982.
  12. Withers. John. Dong. Xinnian. 2016-08-11. Zipfel. Cyril. Posttranslational Modifications of NPR1: A Single Protein Playing Multiple Roles in Plant Immunity and Physiology. PLOS Pathogens. en. 12. 8. e1005707. 10.1371/journal.ppat.1005707. 1553-7374. 4981451. 27513560 . free .
  13. News: http://www.sohu.com/a/207865345_355701 . zh:王小凡和董欣年：中美院士伉俪竟是武大同学 . Sohu . 2017-12-01 . zh.
  14. News: http://www.bio.whu.edu.cn/index.php/View/2619.html . zh:杰出校友王小凡、董欣年教授重回母校 . whu.edu.cn . 2018-06-13 . zh.
  15. News: China Daily Website - Connecting China Connecting the World . zh:董欣年的珞珈情缘 . Chinadaily . 2012-07-02 . zh.
  16. Web site: 2015. The World's Most Influential Scientific Minds - 2015.

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