XhoI explained

Symbol:XhoI
XhoI
Pfam:PF04555
Interpro:IPR007636

In molecular biology, XhoI is a type II restriction enzyme EC that recognise the double-stranded DNA sequence CTCGAG and cleaves after C-1.[1] Type II restriction endonucleases (EC) are components of prokaryotic DNA restriction-modification mechanisms that protect the organism against invading foreign DNA. These site-specific deoxyribonucleases catalyse the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

Notes and References

  1. Theriault G, Roy PH, Howard KA, Benner JS, Brooks JE, Waters AF, Gingeras TR . Nucleotide sequence of the PaeR7 restriction/modification system and partial characterization of its protein products . Nucleic Acids Res. . 13 . 23 . 8441–61 . December 1985 . 3001639 . 322144 . 10.1093/nar/13.23.8441.