Xanthomonas sRNA explained

In molecular biology, Xanthomonas sRNA are small RNAs which have been identified in various species of the bacterium Xanthomonas.

Analysis of the plant pathogen Xanthomonas campestris pv. vesicatoria revealed expression of seven cis-encoded antisense RNAs (asX1-asX7) and 15 intergenic sRNAs (sX1 - sX15). Several sRNAs have also been identified in Xanthomonas campestris pathovar campestris. Some of these X. campestris sRNAs are only found in Xanthomonas, some are also expressed in other bacteria.^{[1] [2]} Several of these sRNAs appear to contribute to virulence, including sX12, sX13 and sRNA-Xcc1.^{[3] [4]}

Computational analysis predicts 63 sRNAs in Xanthomonas oryzae pathovar oryzae, expression of 8 of these has been experimentally confirmed. Expression of three of these is Hfq-dependent.^[5]

See also

• Bacillus subtilis BSR sRNAs
• Bacterial small RNA
• Escherichia coli sRNA
• Mycobacterium tuberculosis sRNA
• Pseudomonas sRNA

Notes and References

1. Schmidtke C, Findeiß S, Sharma CM, Kuhfuß J, Hoffmann S, Vogel J, etal . Genome-wide transcriptome analysis of the plant pathogen Xanthomonas identifies sRNAs with putative virulence functions. . Nucleic Acids Res . 2011 . 40. 5. 2020–31. 22080557 . 10.1093/nar/gkr904 . 3300014.
2. Jiang RP, Tang DJ, Chen XL, He YQ, Feng JX, Jiang BL, etal . Identification of four novel small non-coding RNAs from Xanthomonas campestris pathovar campestris. . BMC Genomics . 2010 . 11 . 316 . 20482898 . 10.1186/1471-2164-11-316 . 2996969 . free .
3. Chen XL, Tang DJ, Jiang RP, He YQ, Jiang BL, Lu GT, etal . sRNA-Xcc1, an integron-encoded transposon- and plasmid-transferred trans-acting sRNA, is under the positive control of the key virulence regulators HrpG and HrpX of Xanthomonas campestris pathovar campestris. . RNA Biol . 2011 . 8 . 6 . 947–953. 21941121 . 10.4161/rna.8.6.16690. 3256417.
4. Schmidtke. C. Abendroth, U . Brock, J . Serrania, J . Becker, A . Bonas, U . Small RNA sX13: A Multifaceted Regulator of Virulence in the Plant Pathogen Xanthomonas.. PLOS Pathogens. Sep 2013. 9. 9. e1003626. 24068933. 10.1371/journal.ppat.1003626 . 3771888. free.
5. Liang H, Zhao YT, Zhang JQ, Wang XJ, Fang RX, Jia YT . Identification and functional characterization of small non-coding RNAs in Xanthomonas oryzae pathovar oryzae. . BMC Genomics . 2011 . 12 . 87 . 21276262 . 10.1186/1471-2164-12-87 . 3039613 . free .