XCL2 explained

Chemokine (C motif) ligand 2 (XCL2) is a small cytokine belonging to the XC chemokine family that is highly related to another chemokine called XCL1.[1] It is predominantly expressed in activated T cells, but can also be found at low levels in unstimulated cells. XCL2 induces chemotaxis of cells expressing the chemokine receptor XCR1.[2] Its gene is located on chromosome 1 in humans.[3]

References

  1. Kennedy J, Kelner G, Kleyensteuber S, Schall T, Weiss M, Yssel H, Schneider P, Cocks B, Bacon K, Zlotnik A . Molecular cloning and functional characterization of human lymphotactin . J Immunol . 155 . 1 . 203–9 . 1995 . 10.4049/jimmunol.155.1.203 . 7602097. free .
  2. Yoshida T, Imai T, Kakizaki M, Nishimura M, Takagi S, Yoshie O . Identification of single C motif-1/lymphotactin receptor XCR1 . J Biol Chem . 273 . 26 . 16551–4 . 1998 . 9632725 . 10.1074/jbc.273.26.16551. free .
  3. Yoshida T, Imai T, Takagi S, Nishimura M, Ishikawa I, Yaoi T, Yoshie O . Structure and expression of two highly related genes encoding SCM-1/human lymphotactin . FEBS Lett . 395 . 1 . 82–8 . 1996 . 8849694 . 10.1016/0014-5793(96)01004-6. free . 1996FEBSL.395...82Y .

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