Wohl–Aue reaction explained

The Wohl–Aue reaction is an organic reaction between an aromatic nitro compound and an aniline to form a phenazine in presence of an alkali base.[1] [2] An example is the reaction between nitrobenzene and aniline:

The reaction is named after Alfred Wohl and W. Aue.

References

  1. Alfred Wohl and W. Aue . Über die Einwirkung von Nitrobenzol auf Anilin bei Gegenwart von Alkali . . 34 . 2442–2450 . 1901 . 10.1002/cber.190103402183 . 2. 2027/uc1.b2652529 . free .
  2. The Wohl-Aue Reaction. I. Structure of Benzo [a] phenazine Oxides and Syntheses of 1,6-Dimethoxyphenazine and 1,6-Dichlorophenazine . Irwin J. Pachter and Milton C. Kloetzel . . 1951 . 73 . 10 . 4958–4961 . 10.1021/ja01154a144.