Tooth and nail syndrome explained

Tooth and nail syndrome (also known as "Hypodontia with nail dysgenesis," and "Witkop syndrome") is a rare disorder, first described in 1965, characterized by nails that are thin, small, and friable, and which may show koilonychia at birth.^{[1] [2]}

It is associated with MSX1.^[3]

See also

• Skin lesion
• List of cutaneous conditions

Notes and References

1. Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. .
2. Book: Rapini, Ronald P. . Bolognia, Jean L. . Jorizzo, Joseph L. . Dermatology: 2-Volume Set . Mosby . St. Louis . 2007 . 880 . 978-1-4160-2999-1 .
3. Jumlongras D, Bei M, Stimson JM, etal . A nonsense mutation in MSX1 causes Witkop syndrome . Am. J. Hum. Genet. . 69 . 1 . 67–74 . July 2001 . 11369996 . 1226049 . 10.1086/321271 .