| Wilson Run | |
| Name Other: | Tributary to Brandywine Creek |
| Map Size: | 180 |
| Pushpin Map: | USA Delaware |
| Pushpin Map Size: | 180 |
| Pushpin Map Caption: | Location of Wilson Run mouth |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | Delaware |
| Subdivision Type3: | County |
| Subdivision Name3: | New Castle |
| Length: | 2.26miles[1] |
| Discharge1 Location: | Brandywine Creek |
| Discharge1 Avg: | 5.17cuft/s at mouth with Brandywine Creek[2] |
| Source1: | divide between Brandywine Creek and Red Clay Creek |
| Source1 Location: | about 0.5 miles south of Centerville, Delaware[3] |
| Source1 Coordinates: | 39.8169°N -75.6203°W[4] |
| Source1 Elevation: | 340feet |
| Mouth: | Brandywine Creek |
| Mouth Location: | Rockland, Delaware |
| Mouth Coordinates: | 39.7967°N -75.5753°W |
| Mouth Elevation: | 118feet |
| Progression: | southeast |
| River System: | Christina River |
| Tributaries Left: | unnamed tributaries |
| Tributaries Right: | unnamed tributaries |
Wilson Run is a 2.26miles long tributary to Brandywine Creek in New Castle County, Delaware. Wilson Run drains the Winterthur area of Delaware.